Improved Identification of Host Cell Proteins in Monoclonal Antibodies by Combining Filter Aided Sample Preparation and Native Digestion
Yang Yang, Jing Wu, Fang Wang, Mark Lefers
This paper improves HCP identification in monoclonal antibodies by combining FASP and native digestion with shotgun proteomics, achieving higher sensitivity and broader molecular weight coverage.
Journal of Pharmaceutical Sciences · Jun 15, 2025Peer-reviewedBiochemistry