Distinct mutational landscapes when comparing germline and somatic cancer variants in forty tumor suppressor genes.
Suhasini D. Lulla, Deborah Ritter, Chimene A. Kesserwan, Sharon E. Plon
The paper compares germline and somatic variants in 40 tumor suppressor genes, finding distinct mutational patterns and locations shaped by different selection pressures.
bioRxiv · Feb 28, 2026 · PreprintGenetics