Author

Shannon L. Gourley

Emory UniversityORCID 0000-0002-7783-9379Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:deconvolution· 1 Approach:deep learning· 1

Frequent Co-Authors

Peng JiniD· 2 shared Sumeet K. SharmaiD· 2 shared Zhaohui Steve QiniD· 2 shared Dan C. LiiD· 1 shared Gracy Trinoskey-RiceiD· 1 shared Henry W. KietzmaniD· 1 shared Jidong GuoiD· 1 shared Kerry James RessleriD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Peng JinORCID

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3 papers

Recent·Most cited

Dysregulation of Prefrontal Oligodendrocyte Lineage Cells Across Mouse Models of Adversity and Human Major Depressive Disorder

Sumeet K. Sharma, Wenjing Ma, Kerry James Ressler, Thea Anderson, Dan C. Li, Peng Jin, Shannon L. Gourley, Zhaohui Steve Qin

The paper identifies conserved oligodendrocyte dysregulation in mouse adversity models and human MDD, linking it to behavioral deficits and frontal cortex dysfunction.

bioRxiv · Mar 9, 2023 · PreprintNeuroscience

LRcell: detecting the source of differential expression at the sub-cell type level from bulk RNA-seq data

Wenjing Ma, Sumeet K. Sharma, Peng Jin, Shannon L. Gourley, Zhaohui Steve Qin

LRcell identifies sub-cell types responsible for differential expression in bulk RNA-seq by using precomputed marker genes from scRNA-seq data, outperforming existing deconvolution methods.

Briefings in Bioinformatics · Feb 9, 2022Peer-reviewedBioinformatics

Cell adhesion factors during adolescence support amygdalo-cortical connections and flexible action later in life

Henry W. Kietzman, Lauren P. Shapiro, Gracy Trinoskey-Rice, Jidong Guo, Shannon L. Gourley

This study shows that β1-integrin in adolescent prefrontal cortex is necessary for adult mice to select actions based on reward value through amygdalo-cortical circuits.

bioRxiv · Jul 12, 2021 · PreprintNeuroscience