ZC3H11A mutations cause high myopia by triggering PI3K-AKT and NF-κB mediated signaling pathway in humans and mice
Chong Chen, Qian Liu, Cheng Cai Tang, Yu Rong, Xinyi Zhao, Dandan Li, Fan Lü, Jia Qu, Xinting Liu
This study identifies ZC3H11A mutations as a cause of high myopia in humans and mice, showing their impact on PI3K-AKT and NF-κB signaling pathways.
eLife · Aug 27, 2025Peer-reviewedGenetics