CHONG CHEN

Genetically Encoded Melanin as a Photostable Scattering Contrast for Whole-Brain Tomography

The paper introduces MelaCAST, a genetically encoded scattering method for whole-brain imaging in mice, providing photostable contrast without photobleaching.

High-throughput whole-brain scattering imaging resolves Amyloid plaques through clearing-assisted contrast modulation

This paper introduces CAST, a label-free whole-brain imaging technique that maps amyloid plaques in mouse brains using clearing-assisted scattering tomography.

Deep learning-enabled speckle reduction for cleared-sample coherent scattering tomography

The paper introduces CLEAR Net, a deep learning method to reduce speckle noise in CAST brain imaging while preserving structural details, and benchmarks it against existing methods.

FUSION: A fast and uniform processing framework for whole-brain optical scattering tomography images

The paper introduces FUSION, a framework for processing whole-brain optical scattering tomography images, enabling high-throughput and uniform stitching of fuCAST datasets.

ZC3H11A mutations cause high myopia by triggering PI3K-AKT and NF-κB mediated signaling pathway in humans and mice

This study identifies ZC3H11A mutations as a cause of high myopia in humans and mice, showing their impact on PI3K-AKT and NF-κB signaling pathways.

Graph theory analysis reveals an assortative pain network vulnerable to attacks

The paper uses graph theory to analyze the structural pain network, revealing it is assortative and vulnerable to attacks on hub nodes.