Increased Aperiodic Exponents Track Depression Symptom Severity
Mark R. Libowitz, Wendy Sun, Rebecca J. Rabinovich, Jingnan Du, Justin M. Campbell, Rhiannon L Cowan, Niloufar Shahdoust, T. Alexander Price, Tyler S. Davis, Randy L. Buckner, Shervin Rahimpour, Brian J. Mickey, Elliot H. Smith, Ben Shofty
This study shows that aperiodic exponents from intracranial EEG can differentiate depression symptom severity and correlate with specific brain regions and networks.
bioRxiv · Mar 6, 2026 · PreprintNeuroscience