ImmunologyGastroenterologyPeer-reviewed
TL1A/DR3 signaling regulates the generation of pathogenic Th9 cells in experimental inflammatory bowel disease
Paola Menghini, Ludovica F. Buttó, Adrian Gomez-Nguyen…·Fabio Cominelli
This study shows that DR3 signaling promotes Th9 cell pathogenicity in CD-like ileitis by enhancing pro-inflammatory signatures and reducing anti-inflammatory responses.
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