Author

Harish Srinivasan

University of ChicagoORCID 0000-0002-7862-1953Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Jian ZhouiD· 1 shared Jing ZhangiD· 1 shared Qian CongiD· 1 shared Rongqing YuaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBioinformatics

Jian ZhouORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintAug 1, 2026

✦ In-depth digest

Modeling the structure-conditioned sequence landscape for large-scale protein design with TriFlow

Harish Srinivasan, Rongqing Yuan, Jing Zhang…·Jian Zhou

TriFlow, discrete flow-matching sequence designer with global three-track structure attention, raises in silico binder success over ProteinMPNN in RFdiffusion and BindCraft-style pipelines on 500 targets and flags functional sites.

2 citations

humanprotein structure

𝕏 PostBluesky