Data-optimal scaling of paired antibody language models
Mahdi Shafiei Neyestanak, Sarah M. Burbach, Karenna Ng, Praneeth Gangavarapu, Jonathan Hurtado, Judie Magura, Nasreen Ismail, Daniel Muema, Thumbi Ndung’u, Andrew B. Ward, Bryan S. Briney
This study derives a scaling law for antibody language models, showing that performance improvements require both large model size and sufficient data.
bioRxiv · Sep 2, 2025 · PreprintImmunology