Quencher-free fluorescence monitoring of G-Quadruplex folding
Zachary Parada, Tanner G. Hoog, Katarzyna P. Adamala, Aaron E. Engelhart
This paper demonstrates a cost-effective method to monitor G-quadruplex folding transitions using single-dye labeled DNA sequences without quenchers, enabling faster and cheaper synthetic biology applications.
bioRxiv · Jan 31, 2024Biophysics