Anti-correlation of LacI association and dissociation rates observed in living cells
Vinodh K. Kandavalli, Spartak Zikrin, Johan Elf, Daniel Jones
The paper measures association and dissociation rates of LacI binding sites in living cells and finds an anti-correlation between these rates, challenging the assumption that binding site strength is solely determined by dissociation rate.
Nature Communications · Jan 17, 2025Peer-reviewedBiophysics