Author

Chase D. Lindeboom

University of MichiganORCID 0000-0002-7930-2962Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

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Lydia FreddolinoiD· 1 shared Scott A. ScholziD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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Lydia FreddolinoORCID

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1 paper

Recent·Most cited

Genetic context effects can override canonical cis regulatory elements in Escherichia coli

Scott A. Scholz, Chase D. Lindeboom, Lydia Freddolino

The paper shows that low GC-content flanking sequences and proximity to ribosomal RNA operons significantly reduce gene expression in E. coli, independent of regulatory elements.

Nucleic Acids Research · Sep 2, 2022Peer-reviewedSystems Biology