Author

Amanda Forde

Ollscoil na Gaillimhe – University of GalwayORCID 0000-0002-7940-3413Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:GWAS summary statistics· 2 Approach:statistical model· 2 Research Focus:GWAS / association mapping· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Gibran HemaniiD· 2 shared John P. FergusoniD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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2 shared papersGenetics

Gibran HemaniORCID

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2 papers

Recent·Most cited

Simulated sample splitting approach to address biases due to instrument selection and participant overlap in two-sample Mendelian Randomization studies

Amanda Forde, Gibran Hemani, John P. Ferguson

The paper introduces MR-SimSS, a method to correct biases in two-sample MR studies by simulating independent data subsets from GWAS summary statistics, improving causal inference accuracy.

PLoS Genetics · May 8, 2026Peer-reviewedGenetics

Review and further developments in statistical corrections for Winner's Curse in genetic association studies

Amanda Forde, Gibran Hemani, John P. Ferguson

This paper reviews and improves statistical methods to correct for Winner's Curse in GWAS by evaluating simulated and real data, proposing a bootstrap method, and providing an R package.

PLoS Genetics · Sep 18, 2023Peer-reviewedGenetics