Author

Meagan Belcher Dufrisne

Columbia University Irving Medical CenterORCID 0000-0002-7961-4405Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ana M. Esteves· 1 shared Anthony A. KossiakoffiD· 1 shared Brian KlossiD· 1 shared Chelsea M. BrowniD· 1 shared Cristina G. TimóteoiD· 1 shared Filippo ManciaiD· 1 shared Helena SantosiD· 1 shared Nuno BorgesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ana M. Esteves

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedApr 29, 2025

Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE

Yaqi Liu, Chelsea M. Brown, Nuno Borges…·Filippo Mancia

This study determines the cryo-EM structures of PimE from Mycobacterium abscessus and elucidates its mechanism of action, providing insights for anti-TB drug development.

5 citations

cryo-EMexperimental assay

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