Andreas Futschik

Causal analysis of rock-biodiversity relationships over the global Phanerozoic challenges rock record bias and common cause hypothesis

This study evaluates the causes of covariation between marine biodiversity and sedimentary rock quantity over the Phanerozoic, finding that rock-record bias and common-cause mechanisms both contribute, but neither fully explains the patterns.

Pleiotropy increases parallel selection signatures during adaptation from standing genetic variation

The paper examines how pleiotropy influences parallel gene expression evolution in Drosophila simulans adapted to a new temperature regime, finding both direct and indirect effects of pleiotropy on parallelism.

Haplotype based testing for a better understanding of the selective architecture

The paper introduces a haplotype-based testing method for detecting selection in population genetics, showing higher power and better understanding of selective signatures compared to allele frequency approaches.

Bayesian linear models with unknown design over finite alphabets

The paper introduces a hierarchical Bayesian method for reconstructing unknown matrices in a multivariate linear model with binary entries and a weight matrix, addressing permutation identifiability through order-preserving shrinkage priors.

Multiple Haplotype Reconstruction from Allele Frequency Data

This paper introduces haploSep, a method to infer haplotypes and their frequencies from allele frequency data, improving accuracy and enabling multi-haplotype estimation.

LDJump: Estimating Variable Recombination Rates from Population Genetic Data

LDJump estimates historical recombination rates and identifies hotspots using a sequential multiscale change point estimator, validated on human genome data.

Length asymmetry and heterozygosity strongly influences the evolution of poly-A microsatellites at meiotic recombination hotspots

The paper investigates how length asymmetry and heterozygosity affect poly-A microsatellite evolution at meiotic recombination hotspots, finding deletion and insertion biases based on allele length differences.