Angelika Lahnsteiner

This study examines how substrate curvature affects osteoblast gene expression over time, showing shifts from immediate-early gene activation to ECM remodeling and signaling changes.

This study shows PRDM9 binds G-quadruplex structures, enhancing meiotic recombination by creating chromatin accessibility.

The paper analyzes single-stranded DNA (ssDNA) formation in human and non-human ape telomere-to-telomere genomes to identify non-B DNA structures and their functional roles.

This study examines the association between six SNPs in the ESR1 gene and premenstrual symptom severity, finding SNP-specific symptom profiles and interaction effects.

The paper investigates DNA methylation changes in GCK and TM6SF2 regions associated with metabolic diseases and hepatocellular carcinoma, revealing their impact on G-quadruplex formation and gene regulation.

The paper introduces PDAL-Seq, a method to detect DNA secondary structures in vivo, and provides a standardized analysis pipeline.

The paper uses duplex sequencing to analyze de novo mutations in sperm DNA from older and younger donors, finding higher mutation frequencies and recurrence in older donors.

LDJump estimates historical recombination rates and identifies hotspots using a sequential multiscale change point estimator, validated on human genome data.