scRNA-seq mixology: towards better benchmarking of single cell RNA-seq analysis methods
Luyi Tian, Xueyi Dong, Saskia Freytag, Kim‐Anh Lê Cao, Shian Su, Abolfazl JalalAbadi, Daniela Amann‐Zalcenstein, Tom S. Weber, Azadeh Seidi, Jafar S. Jabbari, Shalin H. Naik, Matthew E. Ritchie
The paper benchmarks scRNA-seq analysis methods using synthetic datasets generated from mixed cancer cell lines, identifying methods that perform well across tasks like normalization, clustering, and integration.
Nature Methods · May 27, 2019Peer-reviewedBioinformatics