GenomicsbioRxivPreprint
An invariant network architecture with broadly expressed regulators distinguishes cell-type from cell-state identity in situ
Rui Zhou, Li Ge, Jing Li…·Zhifeng Shao
The paper constructs state-level regulatory networks in mouse liver hepatocytes, revealing an invariant sub-network of broadly expressed TFs that defines cell-type identity, distinct from state-specific variations.