Whole genome sequencing based differentiation between re-infection and relapse in Indian patients with tuberculosis recurrence, with and without HIV co-infection
Sivakumar Shanmugam, Nathan L. Bachmann, Elena M. Martinez, Ranjeeta Menon, Gopalan Narendran, Sujatha Narayanan, Srikanth Prasad Tripathy, Uma Devi Ranganathan, Shailendra Sawleshwarkar, Ben J. Marais, Vitali Sintchenko
This study uses whole genome sequencing to differentiate between TB relapse and re-infection in HIV-positive and negative patients, finding 95% relapse in HIV-negative and 75% re-infection in HIV-positive cases.
International Journal of Infectious Diseases · Mar 18, 2021Peer-reviewedGenomics