Michael Pudjihartono

Mendelian randomizations with spatial gene networks reveal shared and distinct drivers of risk in major skin cancer types

This study uses Mendelian randomization with spatial gene networks to identify causal genes and shared/distinct drivers of risk for melanoma, BCC, and SCC.

Melanoma-specific mutation hotspots in distal, non-coding, promoter-interacting regions implicate novel candidate driver genes

The paper identifies melanoma-specific mutation hotspots in non-coding regions that affect gene expression and suggest novel candidate driver genes.