Author

Agustina Ganuza

Consejo Nacional de Investigaciones Científicas y TécnicasORCID 0000-0002-8093-0683Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Constanza CristaldiiD· 3 shared Laura VanagasiD· 3 shared Sergio Oscar AngeliD· 3 shared Andrés M. AlonsoiD· 2 shared William J. SullivaniD· 2 shared Ana M. Saldarriaga CartagenaiD· 1 shared Ayelén A. Aparicio Arias· 1 shared Ayelén Aparicio AriasiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCell Biology

Constanza CristaldiORCID

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3 papers

Recent·Most cited

Histone H2A.X contributes to Gene Expression Regulation and Cell-Cycle Progression in Toxoplasma gondii Tachyzoites

Constanza Cristaldi, Sofía Horjales, Leonardo Gualano, Agustina Ganuza, Ayelén A. Aparicio Arias, Luiz Daniel de Barros, William J. Sullivan, Andrés M. Alonso, Sergio Oscar Angel, María E. Francia, Laura Vanagas

This study shows that H2A.X in Toxoplasma gondii is not essential for DNA damage response but regulates cell cycle progression and virulence gene expression.

bioRxiv · Oct 13, 2026 · PreprintCell Biology

Toxoplasma gondii RAD51 recombinase is required to overcome DNA replication stress and its inactivation leads to bradyzoite differentiation

Ana M. Saldarriaga Cartagena, Ayelén Aparicio Arias, Constanza Cristaldi, Agustina Ganuza, M. Micaela Gonzalez, María M. Corvi, William J. Sullivan, Laura Vanagas, Sergio Oscar Angel

This study shows that RAD51 is essential for Toxoplasma gondii tachyzoite replication and that its inhibition leads to replication stress and bradyzoite differentiation.

DNA repair · Aug 1, 2025Peer-reviewedMolecular Biology

A bioinformatic approach for the prediction andfunctional classification of Toxoplasma gondii longnon-coding RNAs

Laura Vanagas, Constanza Cristaldi, Gino La Bella, Agustina Ganuza, Sergio Oscar Angel, Andrés M. Alonso

The paper predicts and functionally classifies long non-coding RNAs in Toxoplasma gondii during differentiation, identifying stage-specific expression and potential roles in DNA damage repair.

Scientific Reports · Nov 12, 2024Peer-reviewedBioinformatics