Programming mRNA decay to modulate synthetic circuit resource allocation
Ophelia S. Venturelli, Mika Tei, Štefan Bauer, Leanne Jade G. Chan, Christopher J. Petzold, Adam P. Arkin
This study shows that programming mRNA decay with MazF can redirect cellular resources to synthetic circuits, enhancing target functions like fluorescent reporter expression and gluconate metabolism.
Nature Communications · Apr 26, 2017Peer-reviewedSynthetic Biology