Author

Yu Guo

Harbin Institute of TechnologyORCID 0000-0002-8109-7515Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Organism:human· 1 Approach:mixed model· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Anastasia A. AnashkinaiD· 1 shared Antao DaiiD· 1 shared Chang XuiD· 1 shared Dehua YangiD· 1 shared Eugene I. ShakhnovichiD· 1 shared Guangfu XueiD· 1 shared Huan NieiD· 1 shared Liran JuaniD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Anastasia A. AnashkinaORCID

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2 papers

Recent·Most cited

BioinformaticsFrontiers in Cell and Developmental BiologyPeer-reviewedAug 3, 2021

N439K variant in spike protein may alter the infection efficiency and antigenicity of SARS-CoV-2 based on molecular dynamics simulation

Wenyang Zhou, Chang Xu, Pingping Wang…·Qinghua Jiang

The paper uses molecular dynamics simulation to analyze how the N439K mutation in SARS-CoV-2's spike protein affects its binding to ACE2 and resistance to neutralizing antibodies.

38 citations

protein structuremixed model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJul 22, 2019

Universal activation mechanism of class A GPCRs

Qingtong Zhou, Dehua Yang, Meng Wu…·Suwen Zhao

The paper identifies a universal activation mechanism for class A GPCRs by analyzing high-resolution structures, linking ligand binding to G protein coupling through TM6 movement.

3 citations

humanprotein structure

𝕏 PostBluesky