Properties of the epigenetic clock and age acceleration
Louis Y. El Khoury, T.J. Gorrie-Stone, Melissa Smart, Amanda Hughes, Yanchun Bao, Alexandria Andrayas, Joe Burrage, Eilis J. Hannon, Meena Kumari B, Jonathan S. Mill, Leonard C. Schalkwyk
The paper examines the properties of the Horvath epigenetic clock in older individuals and finds age acceleration measures are age-dependent and may lead to misleading associations with diseases like Alzheimer's.
bioRxiv · Jul 6, 2018 · PreprintGenomics