TREVI: A Transcriptional Regulation-driven Variational Inference Model to Speculate Gene Expression Mechanism with Integration of Single-cell Multi-omics
Lan Cao, Wenhao Zhang, Feng Zeng, Ying Wang
TREVIXMBD integrates scRNA-seq and scATAC-seq data to model gene regulation, improving cell typing and batch correction while revealing TF-gene regulation variations.
bioRxiv · Nov 22, 2023 · PreprintBioinformatics