Wenhao Zhang

This study identifies HMGA1 as a critical driver of MPN progression to sAML, showing it outperforms existing markers and is targeted by pacritinib to improve survival.

The paper investigates how arousal and task utility interact to influence sustained attention in mice, finding that arousal stabilizes near optimal levels during high task utility.

TREVIXMBD integrates scRNA-seq and scATAC-seq data to model gene regulation, improving cell typing and batch correction while revealing TF-gene regulation variations.

This study presents the haplotype-resolved genome of Ligusticum chuanxiong, identifies enzymes involved in butylphthalide biosynthesis, and reveals its hybrid origin.

This study uses pupil dilation as a biosensor to assess real-time effects of vagus nerve stimulation on brain state in mice.

CIGAR-seq identifies mRNA modification regulators through CRISPR screening and RNA modification readout, revealing NSUN6 as a novel m5C methyltransferase.