Deep learning and alignment of spatially-resolved whole transcriptomes of single cells in the mouse brain with Tangram
Tommaso Biancalani, Gabriele Scalia, Lorenzo Buffoni, Raghav Avasthi, Ziqing Lu, Aman Sanger, Neriman Tokcan, Charles R. Vanderburg, Åsa Segerstolpe, Meng Zhang, Inbal Avraham‐Davidi, Sanja Vicković, Mor Nitzan, Sai Ma, Ayshwarya Subramanian, , Aviv Regev
The paper introduces Tangram, a method that aligns single-nucleus RNA-seq data with spatial data to create an anatomically integrated spatial map of the mouse brain.
Nature Methods · Oct 28, 2021Peer-reviewedGenomics