Author

Matthew W. Wheeler

National Institute of Environmental Health SciencesORCID 0000-0002-8242-2391Unclaimed ORCID profile · follow to get notified of new preprints

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Bioinformatics· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

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Mario MedvedoviciD· 1 shared Sarah E. Davidson-FritziD· 1 shared Scott S. AuerbachiD· 1 shared Siva SivaganesaniD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBioinformatics

Mario MedvedovicORCID

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1 paper

Recent·Most cited

BioinformaticsComputational ToxicologyPeer-reviewedFeb 1, 2022

ALOHA: Aggregated local extrema splines for high-throughput dose-response analysis

Sarah E. Davidson-Fritz, Matthew W. Wheeler, Scott S. Auerbach…·Mario Medvedovic

ALOHA improves dose-response analysis by using Bayesian splines to model gene responses and cluster co-regulated genes, leading to better identification of biological pathways and benchmark doses.

2 citations

bulk RNA-seqstatistical model

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