Author

Lihua Zhang

Chinese Academy of SciencesORCID 0000-0002-8260-7951Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lihua Zhang1 paper

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Organism:human· 1 Research Focus:imputation· 1

Frequent Co-Authors

Shihua ZhangiD· 2 shared

Activity by Year

2019-2020 · peak 1/yr

2 papers

Recent·Most cited

BioinformaticsJournal of Molecular Cell BiologyPeer-reviewedSep 23, 2020

PBLR: an accurate single cell RNA-seq data imputation tool considering cell heterogeneity and prior expression level of dropouts

Lihua Zhang, Shihua Zhang

PBLR imputes dropout events in scRNA-seq data by considering cell heterogeneity and prior expression levels, improving low-dimensional representation and subpopulation detection.

44 citations

scRNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsNucleic Acids ResearchPeer-reviewedMay 22, 2019

Learning common and specific patterns from data of multiple interrelated biological scenarios with matrix factorization

Lihua Zhang, Shihua Zhang

This study introduces CSMF, a matrix factorization framework that combines data dimension reduction and differential analysis to reveal common and specific patterns across interrelated biological scenarios.

46 citations

𝕏 PostBluesky