Depletion of the protein hydration shell with increasing temperature observed by small-angle X-ray scattering and molecular simulations
Johanna-Barbara Linse, Hyun Sun Cho, Friedrich Schotte, Philip Anfinrud, Jochen S. Hub
This study uses SAXS and simulations to show that protein hydration shells shrink with increasing temperature, revealing temperature-sensitive structural changes in the hydration shell.
Journal of the American Chemical Society · Dec 11, 2025Peer-reviewedBiophysics