NeurosciencebioRxivPreprint
ApoE isoforms differentially regulate neuronal membrane proteasomes to shift the threshold for pathological aggregation of endogenous Tau
Victoria Paradise, M Sabu, J Bafia…·KV Ramachandran
This study shows ApoE isoforms modulate neuroproteasome function, affecting Tau aggregation thresholds and contributing to Alzheimer's disease pathology.
10 citations