In pemphigus, cell detachment, but not autoantibody binding, induces cell-wide, long-lasting transcriptomic and proteomic changes
Veronika Hartmann, Sen Guo, Siavash Rahimi, Uta Katharina Radine, Danielle Malheiros, Amanda Salviano‐Silva, Valéria Bumiller‐Bini, Gabriel Adelman Cipolla, Verónica Calonga‐Solís, Axel Künstner, Imke A. K. Burmester, Ralf Joachim Ludwig, William V. J. Hariton, Christoph Matthias Hammers, Eliane J. Müller, , Jennifer E. Hundt
The paper shows that in pemphigus, cell detachment, not autoantibody binding, causes long-term transcriptomic and proteomic changes associated with blister formation.
bioRxiv · Feb 10, 2025 · PreprintImmunology