Author

Whitney Besse

Yale UniversityORCID 0000-0002-8283-1507Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

Albertien M. van EerdeiD· 1 shared Bert van der ZwaagiD· 1 shared Dana Sierks· 1 shared Emilia K. BijlsmaiD· 1 shared Floor Schukking· 1 shared Floranne BoulogneiD· 1 shared Franka E. van Reekum· 1 shared Harm-Jan WestraiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Albertien M. van EerdeORCID

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2 papers

Recent·Most cited

PERADIGM: Phenotype Embedding Similarity-based Rare Disease Gene Mapping

Wangjie Zheng, Yuhan Xie, Jianlei Gu, Hongyu Li, Stefan Somlo, Whitney Besse, Hongyu Zhao

PERADIGM identifies rare disease-associated genes by integrating phenotype embeddings and patient similarity, outperforming traditional methods in detecting candidate genes for ADPKD, Marfan syndrome, and NF1.

PLoS Genetics · Dec 18, 2025Peer-reviewedGenetics

KidneyNetwork: Using kidney-derived gene expression data to predict and prioritize novel genes involved in kidney disease

Floranne Boulogne, Laura R. Claus, Henry H. Wiersma, Roy Oelen, Floor Schukking, Niek de Klein, Shuang� Li, Harm-Jan Westra, Bert van der Zwaag, Franka E. van Reekum, Dana Sierks, Ria Anne-Rose Schönauer, Zhigui Li, Emilia K. Bijlsma, Willem Jan W. Bos, , Albertien M. van Eerde

KidneyNetwork predicts kidney-specific gene functions and disease phenotypes using co-expression networks, identifying ALG6 as a candidate gene for kidney and liver cysts in undiagnosed patients.

European Journal of Human Genetics · Feb 20, 2023Peer-reviewedGenetic & Genomic Medicine