Triacylglycerol fatty acid composition modulates ATGL regioselectivity and diacylglycerol output
Nadine B. Egger, Thomas Züllig, Karl F. Gruber, Christian C. Gruber, Franz P.W. Radner, Amit Singh Sahrawat
This study shows that ATGL's regioselectivity in cleaving triacylglycerol depends on fatty acid chain length and composition, leading to specific diacylglycerol regioisomers.
bioRxiv · Oct 13, 2026 · PreprintBiochemistry