Advancing long-read metagenomic binning via single-copy-gene guided contrastive learning
Haitao Han, Lauren F. Messer, Christopher Quince, Gary D. Bending, Sébastien Raguideau, Ziye Wang, Shanfeng Zhu
SCGBinner improves long-read metagenomic binning by using single-copy gene guided contrastive learning, outperforming existing methods on real-world datasets and recovering novel microbial species.
bioRxiv · Sep 9, 2026 · PreprintBioinformatics