Droplet-assisted folding of long regulatory RNAs
Simon Doll, Lukáš Pekárek, Fathima Hisana Ferosh, Jovana Vasiljević, Tyler S. Harmon, Marcus Jahnel
The paper proposes a mechanism called droplet-assisted RNA folding, where RNA-binding protein condensates guide the folding of long regulatory RNAs by preventing premature interactions and enabling long-range contacts.
bioRxiv · Sep 15, 2025 · PreprintMolecular Biology