BioinformaticsJournal of Pharmaceutical AnalysisPeer-reviewed
Combining transformer and 3DCNN models to achieve co-design of structures and sequences of antibodies in a diffusional manner
Yue Hu, Feng Tao, Jiajie Xu…·Wei Lan
The paper introduces AlphaPanda, an algorithm combining transformer, 3DCNN, and diffusion models for antibody sequence and structure design, achieving high-quality results with reduced training data.