Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin
Qian Xiao, Joseph Mears, Aparna Nathan, Kazuyoshi Ishigaki, Yuriy Baglaenko, Noha Lim, Laura A. Cooney, Kristina M. Harris, Mark Stuart Anderson, David A. Fox, Dawn Elaine Smilek, James G. Krueger, Soumya Raychaudhuri
This study identifies eQTLs in psoriatic skin that are modulated by local inflammation, showing that gene regulation is primarily influenced by skin-specific factors rather than systemic variables.
Nature Communications · Oct 7, 2023Peer-reviewedGenetic & Genomic Medicine