Author

Joshua D. Love

ORCID 0000-0002-8485-6740Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 4 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:software / tool· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Simon d’OelsnitziD· 5 shared Andrew D. EllingtoniD· 3 shared Michael SpringeriD· 2 shared Nicole N ZhaoiD· 2 shared Pamela A. SilveriD· 2 shared Pranay TallaiD· 2 shared Brady Michael RaffertyiD· 1 shared Daniel J. DiaziD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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5 shared papersSynthetic Biology

Simon d’OelsnitzORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Ligify 2.0: A web server for predicted small molecule biosensors

Simon d’Oelsnitz, Nicole N Zhao, Pranay Talla, Jio Jeong, Joshua D. Love, Michael Springer, Pamela A. Silver

Ligify 2.0 predicts small molecule interactions with transcription factors and provides a web interface for visualization and biosensor design.

Nucleic Acids Research · Apr 28, 2026Peer-reviewedBioengineering

groovDB in 2025: A community-editable database of small molecule biosensors

Joshua D. Love, Brady Michael Rafferty, Michael Thomas, Nicole N Zhao, Pranay Talla, Michael Springer, Pamela A. Silver, Simon d’Oelsnitz

groovDB is updated to be community-editable with enhanced features, doubling its TF entries and making source code open-access.

bioRxiv · Aug 18, 2025 · PreprintSynthetic Biology

Ligify: Automated genome mining for ligand-inducible transcription factors

Simon d’Oelsnitz, Joshua D. Love, Andrew D. Ellington, David Ross

Ligify predicts transcription factors responsive to user-defined chemicals and generates plasmids for biosensor development, achieving 31/100 correct predictions in benchmarking.

ACS Synthetic Biology · Jul 19, 2024Peer-reviewedSynthetic Biology

Snowprint: a predictive tool for genetic biosensor discovery

Simon d’Oelsnitz, Sarah K. Stofel, Joshua D. Love, Andrew D. Ellington

Snowprint predicts regulator:DNA interactions and designs promoters for uncharacterized regulators, enabling the discovery of new biosensors for various compounds.

Communications Biology · Feb 9, 2024Peer-reviewedSynthetic Biology

GroovDB: A database of ligand-inducible transcription factors

Simon d’Oelsnitz, Joshua D. Love, Daniel J. Diaz, Andrew D. Ellington

GroovDB is a database of ligand-inducible transcription factors that provides curated data for building chemically-responsive genetic circuits.

ACS Synthetic Biology · Sep 30, 2022Peer-reviewedSynthetic Biology