Cell BiologyAngewandte Chemie International EditionPeer-reviewed
Modular Design and Scaffold-Synthesis of Multi-Functional Fluorophores for Targeted Cellular Imaging and Pyroptosis
Lei Zhang, Chunhui Wang, Yuanyuan Li…·Thorben Cordes
This study designs and synthesizes functional fluorophores using a scaffold-based Ugi reaction, enabling detection of reactive-oxygen species and controlled subcellular localization, with some compounds showing pyroptosis-inducing activity in cancer cells.
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