Author

André Poisl Fay

Dana-Farber Cancer InstituteORCID 0000-0002-8588-7012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alexander GuseviD· 2 shared Ji-Heui SeoiD· 2 shared Mark M. PomerantziD· 2 shared Matthew L. FreedmaniD· 2 shared Bogdan PaşaniuciD· 1 shared Cassandra Singler· 1 shared Chia-Chi Flora HuangiD· 1 shared Christopher J. SweeneyiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Alexander GusevORCID

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2 papers

Recent·Most cited

Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation

Sylvan C. Baca, Cassandra Singler, Soumya Zacharia, Ji-Heui Seo, Tunç Morova, Faraz Hach, Yi Ding, Tommer Schwarz, Chia-Chi Flora Huang, Jacob Anderson, André Poisl Fay, Cynthia A. Kalita, Stefan Groha, Mark M. Pomerantz, Victoria Wang, , Matthew L. Freedman

The paper introduces CWAS, a method linking genetic variation to chromatin states, identifying novel prostate cancer risk loci and regulatory mechanisms not detectable by eQTLs.

Nature Genetics · Sep 1, 2022Peer-reviewedGenetics

Allelic imbalance reveals widespread germline-somatic regulatory differences and prioritizes risk loci in Renal Cell Carcinoma

Alexander Gusev, Sándor Spisák, André Poisl Fay, Hallie A. Carol, Kevin C. Vavra, Sabina Signoretti, Viktória Tisza, Mark M. Pomerantz, Forough Abbasi, Ji-Heui Seo, Toni K. Choueiri, Kate Lawrenson, Matthew L. Freedman

The paper identifies allele-specific quantitative trait loci (asQTLs) in RCC, showing their enrichment in GWAS risk loci and linking them to hypoxia pathway interactions.

bioRxiv · May 8, 2019 · PreprintGenetics