Profiling of circulating chromosome 21-encoded microRNAs, miR-155 and Let-7c, in Down Syndrome People
Jesús M. Peréz-Villarreal, Katia Aviña‐Padilla, Evangelina Beltrán‐López, Alma Marlene Guadrón‐Llanos, Esther López‐Bayghen, Javier A. Magaña‐Gómez, Marco Antonio Meraz‐Ríos, Alfredo Varela‐Echavarría, Carla Angulo‐Rojo
This study examines miR-155 and Let-7c expression in Down syndrome individuals and finds Let-7c overexpression linked to early cognitive impairment, while miR-155 correlates with lipid metabolism changes in adults.
Molecular Genetics & Genomic Medicine · Apr 12, 2022Peer-reviewedGenetic & Genomic Medicine