Alfredo Varela‐Echavarría

The neurovascular unit of capillary blood vessels in the rat nervous system. A rapid-Golgi electron microscopic study.

The paper describes a pericapillary organ in the rat nervous system composed of tripartite synapses and astrocytic endfeet, suggesting a mechanoreceptor role and presynaptic modulation by Piezo 1 mRNA.

Profiling of circulating chromosome 21-encoded microRNAs, miR-155 and Let-7c, in Down Syndrome People

This study examines miR-155 and Let-7c expression in Down syndrome individuals and finds Let-7c overexpression linked to early cognitive impairment, while miR-155 correlates with lipid metabolism changes in adults.

SARS-CoV-2 Entry Protein TMPRSS2 and Its Homologue, TMPRSS4 Adopts Structural Fold Similar to Blood Coagulation and Complement Pathway Related Proteins

This study analyzes the amino acid sequences and predicted 3D structures of TMPRSS2 and TMPRSS4, revealing structural similarities to blood coagulation proteins and suggesting potential therapeutic targets for COVID-19.

On the existence of mechanoreceptors within the neurovascular unit of the rodent and rabbit brain

The paper identifies perivascular interneurons and fibro-vesicular complexes in rodent and rabbit brains, suggesting they function as mechanoreceptors within the neurovascular unit.