The paper compares genomic differences between DNase-producing and non-producing Streptococcus agalactiae strains to identify genetic factors associated with DNase activity and virulence.

Infection Genetics and Evolution · Jun 18, 2021Peer-reviewedGenomics

Global gene expression analysis of Streptococcus agalactiae at exponential growth phase

Inês Silvestre, Vítor Borges, Sílvia Duarte, Alexandra Nunes, Rita Gonçalves Sobral, Luís Vieira, João Paulo Gomes, Maria José Borrego

The paper performs RNA-sequencing to analyze global gene expression of S. agalactiae NEM316 during exponential growth, identifying translation-related genes and highlighting gaps in understanding DNase release mechanisms.

bioRxiv · Nov 13, 2020 · PreprintGenomics

Chlamydia trachomatis outbreak: when the virulence-associated genome backbone imports a prevalence-associated major antigen signature

Vítor Borges, Dora Cordeiro, Ana Isabel Salas, Zohra Lodhia, Cristina Belo Correia, Joana Isidro, Cândida Fernandes, Ana Maria Rodrigues, Jacinta Azevedo, João Alves, João Rôxo, Miguel Rocha, Rita Côrte‐Real, Luı́s Vieira, Maria José Borrego, João Paulo Gomes

The paper reports an outbreak of Chlamydia trachomatis caused by a hybrid L2b/D-Da strain with a unique genome that combines virulence features of LGV and non-LGV strains.

Microbial Genomics · Nov 1, 2019Peer-reviewedGenomics