Normalizing LZ+ MYPT1 Expression Prevents the Development of HFpEF
Young Soo Han, Teresa M. Pfiefer, Bin Zhang, Matthew Joseph Fogarty, Gary Charles Sieck, Frank V. Brozovich
This study shows that maintaining normal LZ+ MYPT1 expression prevents HFpEF development in mice by improving vascular reactivity and diastolic function.
bioRxiv · Aug 25, 2026 · PreprintPhysiology