Author

Christopher J Adams

University of PennsylvaniaORCID 0000-0002-8615-9164Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Christopher J Adams1 paper · Imperial College London

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

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Benjamin F. VoightiD· 1 shared Benjamin J. AuerbachiD· 1 shared Iain MathiesoniD· 1 shared Mitchell ConeryiD· 1 shared Shane T. JenseniD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperGenomics

Benjamin F. VoightORCID

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1 paper

Recent·Most cited

GenomicsPLoS GeneticsPeer-reviewedJul 7, 2023

Regularized sequence-context mutational trees capture variation in mutation rates across the human genome

Christopher J Adams, Mitchell Conery, Benjamin J. Auerbach…·Benjamin F. Voight

Baymer is a Bayesian hierarchical model that estimates mutation probabilities using sequence context, showing improved accuracy and robustness compared to previous methods.

11 citations

humanwhole-genome sequencing

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