Author
University of WashingtonORCID 0000-0002-8657-7964Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Brian E. Cade, Jiwon Lee, Tamar Sofer…·Scott E. Devine
The paper reports whole-genome association analyses of sleep-disordered breathing traits in the NHLBI TOPMed program, identifying rare and common variant associations.
Han Chen, Jennifer E. Huffman, Jennifer A. Brody…·Xihong Lin
The paper introduces SMMAT, a variant-set mixed model association test for continuous and binary traits in large-scale WGS studies, showing it controls type I error rates and applies to population structured and related samples.
Pradeep Natarajan, Gina Marie Peloso, Seyedeh Maryam Zekavat…·Sayantan Das
The paper analyzes whole genome sequences from 16,324 individuals to identify genetic variants associated with blood lipid levels and develops a polygenic score for LDL-C.
Seyedeh Maryam Zekavat, Sanni Ruotsalainen, Robert E. Handsaker…·Brian Custer
The paper uses whole genome sequencing to identify genetic variants associated with plasma lipoprotein(a) levels and finds high heritability and inter-ethnic differences in Lp(a) risk.
The International Genomics of Alzheimer's Project, Kuan-lin Huang, The Alzheimer's Disease Neuroimaging Initiative…·Alison Goate
This study identifies a haplotype lowering PU.1 expression in myeloid cells that delays Alzheimer’s disease onset by affecting gene expression and function.
Evan K. Maxwell, Jonathan S. Packer, Colm T. O’Dushlaine…·Jeffrey G. Reid
The paper identifies and analyzes exonic copy number variants (CNVs) in 50,726 DiscovEHR participants, linking them to clinical traits and phenotypes.