Horizontal gene transfer by plasmids relaxes the evolutionary constraints of its own tradeoff
Olivia Kosterlitz, Elizabeth S. Duan, Maya Abhyankar, Benjamin Kerr, Eva Maria Top
The paper examines the evolutionary tradeoff between horizontal and vertical gene transfer in plasmids, finding mixed evidence and proposing that HGT relaxes constraints by introducing plasmids into novel hosts.
bioRxiv · Jun 3, 2026 · PreprintEvolutionary Biology