Mosaic chromosomal alterations in blood across ancestries via whole-genome sequencing
Yasminka A. Jakubek, Ying Zhou, Adrienne M. Stilp, Jason Bacon, Justin Wong, Zuhal Özcan, Donna K. Arnett, Kathleen C. Barnes, Joshua C. Bis, Eric Boerwinkle, April P. Carson, Daniel I. Chasman, Michael Cho, Matthew P. Conomos, Nancy Jean Cox, , Paul Livermore Auer
This study uses whole-genome sequencing to analyze mosaic chromosomal alterations across diverse ancestries, finding higher rates in certain populations and associations with germline variants.
bioRxiv · Nov 7, 2022 · PreprintGenomics