Transfer Learning and Permutation-Invariance improving Predicting Genome-wide, Cell-Specific and Directional Interventions Effects of Complex Systems
Boyang Wang, Boyu Pan, Tingyu Zhang, Qingyuan Liu, Shao Li
This paper develops a deep learning model called SETComp to predict intervention effects of complex systems using transfer learning and permutation-invariance, achieving significant accuracy improvements over baselines.
Advanced Science · Sep 19, 2025Peer-reviewedSystems Biology